Proprotein convertases in gynecological cancers /

Bibliographic Details
Main Author:	Klein-Szanto, Andres J. P.
Other Authors:	Bassi, Daniel, Zhang, Jirong
Format:	eBook
Language:	English
Published:	San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : Morgan and Claypool, [2012]
Series:	Colloquium digital library of life sciences. Colloquium series on protein activation and cancer ; # 2.
Subjects:	Cancer in women. Generative organs, Female > Cancer. Protein precursors. Genital Neoplasms, Female. Proprotein Convertases. PACE4 cancer carcinogenesis furin proprotein convertases Electronic books.
Online Access:	Connect to the full text of this electronic book

Description
Abstract:	Gynecological cancers include neoplasias of internal female genital organs, mainly ovarian, endometrial and cervical tumors, and cancers of the external female genital structures. Current scientific evidence indicates that both up- and down-regulation of the expression of PCs are part of the multiple changes occurring in these gynecological tumors. Nevertheless, the physiological significance of this puzzling pattern of PC expression remains elusive. The fact that PCs can activate both pro- and anticarcinogenic substrates may indicate that the nature of the overexpressed substrates in certain cancer types could determine the final outcome; id est, slowing or accelerating cancer development.
Item Description:	Electronic resource. Part of: Colloquium digital library of life sciences. Series from website.
Physical Description:	1 online resource (xi, 35 pages) : illustrations Also available in printing.
Format:	Mode of access: World Wide Web. System requirements: Adobe Acrobat reader.
Bibliography:	Includes bibliographical references (pages 23-30).
ISBN:	9781615044658 (electronic bk.)
DOI:	10.4199/C00065ED1V01Y201208PAC002
Access:	Abstract freely available; full-text restricted to subscribers or individual document purchasers.