Cover Image

The role of proprotein convertases in animal models of skin carcinogenesis /

Bibliographic Details
Other Authors: Bassi, Daniel
Format: eBook
Language:English
Published: San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : Morgan and Claypool, [2012]
Series:Colloquium digital library of life sciences.
Colloquium series on protein activation and cancer ; # 1.
Subjects:
Enzyme inhibitors > Therapeutic use.
Protein precursors.
Squamous cell carcinoma > Treatment.
Carcinoma, Squamous Cell > therapy.
Enzyme Inhibitors > therapeutic use.
Proprotein Convertases.
PACE4
cancer
carcinogenesis
furin
papilloma
proprotein convertases
skin
squamous cell carcinoma
transgenic mice
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • 1. Introduction
  • 1.1 Skin cancer
  • 2. Proprotein convertases in skin
  • 2.1 Expression of proprotein convertases in human skin and cutaneous tumors
  • 2.2 Expression of proprotein convertases in murine skin and skin tumors
  • 3. Animal models of non-melanoma skin carcinogenesis
  • 3.1 Proprotein convertases in experimental skin cancer
  • 4. Transgenic models of proprotein convertase-mediated skin carcinogenesis
  • 4.1 K5-PACE4 transgenic mice
  • 4.1.1 Chemical carcinogenesis
  • 4.1.2 Ultraviolet carcinogenesis
  • 4.2 K5-furin transgenic mice
  • 4.2.1 Chemical carcinogenesis
  • 4.3 Double transgenic mice
  • 4.3.1 Chemical carcinogenesis
  • 5. In vivo inhibition of proprotein convertases
  • 6. Conclusions
  • References
  • Author biography
  • Titles of related interest.