Seizures and the developing brain /

Bibliographic Details
Main Author:	Galanopoulou, Aristea S.
Format:	eBook
Language:	English
Published:	San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : Morgan and Claypool, [2012]
Series:	Colloquium digital library of life sciences. Colloquium series on the developing brain. # 5.
Subjects:	Convulsions. Developmental neurobiology. Infantile spasms. Brain > growth & development. Seizures. Spasms, Infantile. GABA KCC2 NKCC1 chloride cotransporter cognitive impairment epilepsy epileptogenesis seizure Electronic books.
Online Access:	Connect to the full text of this electronic book

Table of Contents:

1. Seizures and epilepsy: definitions, classification, models
1.1 Definitions and classifications
1.2 Developmental equivalence stages of rodents and humans
1.3 Models of seizures and epilepsies
1.3.1 TLE models
1.3.2 Flurothyl model
1.3.3 Kindling model
2. Brain development controls seizure susceptibility and outcomes
2.1 Developmental regulation of factors influencing seizure susceptibility
2.1.1 Neurotransmitter systems
2.1.1.1 Gabaa receptors and brain development
2.1.1.2 Gabaa receptors and seizure susceptibility
2.1.1.3 Other neurotransmitter systems
2.1.2 Subcortical networks controlling seizures
2.2 The importance of age in determining early-life seizure outcomes
2.2.1 Neuronal injury
2.2.2 Mossy fiber sprouting
2.2.3 Gliosis, inflammation, neoneurogenesis
2.2.4 Gene expression changes
2.2.5 Effects of early-life seizures on C1-homeostasis: implications for brain development and epileptogenesis
2.2.6 Early-life seizures and cognitive development
3. Conclusions
References
Author biography.