Intestinal immune system /
| Main Author: | |
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) :
Morgan and Claypool,
[2011]
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| Series: | Colloquium digital library of life sciences.
Colloquium series on integrated systems physiology, from molecule to function. # 25. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Abstract: | In the intestine, a unique immunological system that is different from the systemic immune system exists to provide adaptive immunity in response to luminal bacteria and dietary antigens. There are many lymphoid cell aggregates called gut-associated lymphoid tissue (GALT) including Peyer's patches (PPs), which function as important induction sites for the mucosal immune response. M-cells are present in the epithelium of PPs, having a specialized structure for uptake of macromolecules such as bacteria. In addition to GALT, there are abundant lymphoid cells in the intestinal lamina propria, where they mainly play a role as immune effector cells. A strong innate immune system that mainly consists of dendritic cells, macrophages, and y8T lymphocytes also exists in the intestinal mucosa to assist the barrier function of intestinal epithelial cells. |
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| Item Description: | Electronic resource. Part of: Colloquium digital library of life sciences. Series from website. |
| Physical Description: | 1 online resource (ix, 112 pages) : illustrations Also available in printing. |
| Format: | Mode of access: World Wide Web. System requirements: Adobe Acrobat reader. |
| Bibliography: | Includes bibliographical references (pages 95-112). |
| ISBN: | 9781615041459 (electronic bk.) |
| ISSN: | 2154-5626 ; |
| DOI: | 10.4199/C00037ED1V01Y201107ISP025 |
| Access: | Abstract freely available; full-text restricted to subscribers or individual document purchasers. |