Maternal control of development in vertebrates : my mother made me do it! /
| Main Author: | |
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| Format: | eBook |
| Language: | English |
| Published: |
San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) :
Morgan and Claypool,
[2010]
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| Series: | Colloquium digital library of life sciences.
Colloquium series on developmental biology. # 5. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Abstract: | Eggs of all animals contain mRNAs and proteins that are supplied to or deposited in the egg as it develops during oogenesis. These maternal gene products regulate all aspects of oocyte development, and an embryo fully relies on these maternal gene products for all aspects of its early development, including fertilization, transitions between meiotic and mitotic cell cycles, and activation of its own genome. Given the diverse processes required to produce a developmentally competent egg and embryo, it is not surprising that maternal gene products are not only essential for normal embryonic development but also for fertility. This review provides an overview of fundamental aspects of oocyte and early embryonic development and the interference and genetic approaches that have provided access to maternally regulated aspects of vertebrate development. Some of the pathways and molecules highlighted in this review, in particular, Bmps, Wnts, small GTPases, cytoskeletal components, and cell cycle regulators, are well known and are essential regulators of multiple aspects of animal development, including oogenesis, early embryogenesis, organogenesis, and reproductive fitness of the adult animal. Specific examples of developmental processes under maternal control and the essential proteins will be explored in each chapter, and where known conserved aspects or divergent roles for these maternal regulators of early vertebrate development will be discussed throughout this review. |
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| Item Description: | Electronic resource. Part of: Colloquium digital library of life sciences. Series from website. |
| Physical Description: | 1 online resource (x, 186 pages) : illustrations Also available in printing. |
| Format: | Mode of access: World Wide Web. System requirements: Adobe Acrobat reader. |
| Bibliography: | Includes bibliographical references (pages 157-186). |
| ISBN: | 9781615040520 (electronic bk.) |
| ISSN: | 2155-353X ; |
| DOI: | 10.4199/C00023ED1V01Y201012DEB005 |
| Access: | Abstract freely available; full-text restricted to subscribers or individual document purchasers. |