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00000cam a2200000 a 4500 |
| 001 |
in00003611368 |
| 005 |
20210728125124.0 |
| 006 |
m eo d |
| 007 |
cr cn |||m|||a |
| 008 |
100315s2010 caua foab 000 0 eng d |
| 020 |
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|a 9781615040070 (electronic bk.)
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| 020 |
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|z 9781615040063 (pbk.)
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| 024 |
7 |
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|a 10.4199/C00003ED1V01Y200907CBM003
|2 doi
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| 035 |
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|a (CaBNvSL)gtp00539035
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| 035 |
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|a 200907CBM003
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| 035 |
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|a 5000839
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| 040 |
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|a CaBNvSL
|c CaBNvSL
|d CaBNvSL
|d UtOrBLW
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| 050 |
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4 |
|a QH647
|b .P273 2010
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| 060 |
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4 |
|a QU 375
|b P273a 2010
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| 082 |
0 |
4 |
|a 574.8764
|2 22
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| 100 |
1 |
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|a Pardee, Joel D.
|0 http://id.loc.gov/authorities/names/n2010184225
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| 245 |
1 |
4 |
|a The actin cytoskeleton in cell motility, cancer, and infection /
|c Joel D. Pardee.
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| 264 |
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1 |
|a San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) :
|b Morgan and Claypool,
|c [2010]
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| 264 |
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4 |
|c ©2010
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| 300 |
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|a 1 online resource (xi, 57 pages) :
|b illustrations
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Colloquium series on the cell biology of medicine,
|x 2153-0521 ;
|v # 3
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| 500 |
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|a Electronic resource.
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| 500 |
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|a Part of: Colloquium digital library of life sciences.
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| 500 |
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|a Series from website.
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| 500 |
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|a Title from PDF title page (viewed on March 15, 2010).
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| 504 |
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|a Includes bibliographical references (pages 57).
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0 |
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|a The cytoskeleton -- How cells move -- Regulation of the actin cytoskeleton -- The role of myosin in cell motility -- The role of cell adhesion in cell motility -- Recommended readings.
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|a Abstract freely available; full-text restricted to subscribers or individual document purchasers.
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0 |
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|a Google book search
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| 510 |
0 |
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|a Google scholar
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| 520 |
3 |
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|a By now it is abundantly clear that the cells of our bodies have the ability to move because of their actin cytoskeleton. From the earliest cell migrations in the embryo that serve to form the primordial tissue layers to the outgrowth of neurons, the contractions of our heart and skeletal muscles, and the metastasis of cancer cells, it is the regulated action of the actin cytoskeleton that propels our various motions. In this chapter we will examine the biochemical and cell biological mechanisms that control actin-based cell motility. We will see that cell migration along a substratum occurs in three fundamental phases that are exquisitely orchestrated in sequence. Cell migration occurs by an initial extension of the front edge of the cell, followed closely by contraction of the cell's rear end to push cytoplasm into the newly formed extension. As the cell's new leading edge extends, attachment sites are assembled on the cell floor, and extend through the plasma membrane to couple the migrating cell to the underlying surface. How the cell knows where to go, when to detach and reattach during the migration, and how to keep each process under strict control is a story well worth hearing, because it is motility and adhesion that make a multicellular life such as ours possible.
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| 530 |
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|a Also available in printing.
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| 538 |
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|a Mode of access: World Wide Web.
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| 538 |
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|a System requirements: Adobe Acrobat reader.
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| 650 |
1 |
2 |
|a Actins.
|0 https://id.nlm.nih.gov/mesh/D000199
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| 650 |
1 |
2 |
|a Cell Movement.
|0 https://id.nlm.nih.gov/mesh/D002465
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| 650 |
1 |
2 |
|a Cytoskeleton.
|0 https://id.nlm.nih.gov/mesh/D003599
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| 650 |
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0 |
|a Actin.
|0 http://id.loc.gov/authorities/subjects/sh85000687
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| 650 |
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0 |
|a Cells
|x Motility.
|0 http://id.loc.gov/authorities/subjects/sh85021689
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| 650 |
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0 |
|a Cytoskeleton.
|0 http://id.loc.gov/authorities/subjects/sh85035256
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| 655 |
|
7 |
|a Electronic books.
|2 local
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| 830 |
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0 |
|a Colloquium digital library of life sciences.
|0 http://id.loc.gov/authorities/names/no2014168595
|
| 830 |
|
0 |
|a Colloquium series on the cell biology of medicine.
|x 2153-0521 ;
|v # 3.
|0 http://id.loc.gov/authorities/names/no2009167026
|
| 856 |
4 |
0 |
|u http://proxy.library.tamu.edu/login?url=https://dx.doi.org/10.4199/C00003ED1V01Y200907CBM003
|z Connect to the full text of this electronic book
|t 0
|
| 999 |
f |
f |
|s bb0e3cd3-5acf-384c-9fec-0a289485b518
|i be5216cd-e1a9-38c6-9b38-34298da41184
|t 0
|
| 952 |
f |
f |
|a Texas A&M University
|b College Station
|c Electronic Resources
|d Available Online
|t 0
|e QH647 .P273 2010
|h Library of Congress classification
|
| 998 |
f |
f |
|a QH647 .P273 2010
|t 0
|l Available Online
|