rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Identification of the Regions of the Bovine Genome Associated with Gray Coat Color in a Nellore-Angus Cross Population
  name:
    name part: Holland, Paul W.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Riley, David G.
    role:
      role term: thesis advisor.
  name:
    name part: Texas A & M University
    role:
      role term: degree granting institution.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: txu
    date issued: 2015
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource.
  abstract: The genetics of coat color for cattle are important to breeders and breed associations because phenotypes of these animals are used for breed recognition and premiums or discounts can be given due to the phenotypes. The gene for gray coat color has been determined in other species, but not in cattle. Gray in cattle is known to be recessive based upon observed inheritance. The objective of this study was to identify the regions of the bovine genome associated with gray coat color in a population of Nellore-Angus crossbred cattle. Additionally, proportions of each color and spotting were of interest. Animals (n = 1941) were classified into phenotypic color categories (i.e. red, black, gray, etc.). Proportions of each color group out of the population were determined, and the proportion of those phenotypes that have any form of spotting. Two genome-wide association analyses were conducted, one where phenotypically gray vs. not gray cattle were analyzed and another where cattle that were very light in color but had a reddish tinge were included as gray. Analyses used Bonferroni correction at α = 0.05 (α/ntests = 1.49 x 10^-6). Analysis of gray vs. not gray yielded one significant SNP marker on BTA6 at a location of 68,059,441 bp (Praw = 9.69 x 10^-7, Padjusted = 0.032) (UMD_3.1, NCBI project 32899, Gen Bank GCA_000003055.3). For the analysis of gray and reddish tinged vs. not gray, there were 5 significant markers all on BTA6 forming a region from 62.93 Mb to 83.92 Mb (UMD_3.1, NCBI project 32899, Gen Bank GCA_000003055.3).The same SNP marker from the first analysis was present in the second, but had an increased significance (Praw = 1.50 ̜x 10^-10, Padjusted = 5.02 x 10^-6). The region on BTA6 ruled out syntaxin-17 (STX17) on BTA8 and premelanosome protein (PMEL) on BTA5, previous gray candidate genes from other species, but includes genes such as v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT), which is known to cause white coloration (spotting), a…
  note: by Paul W. Holland.
  note: "Major Subject: Animal Breeding"
  note: Includes vita.
  note: Master of Science Texas A & M University 2015 http://hdl.handle.net/1969.1/155193
  note: Includes bibliographical references.
  note: Text (Thesis)
  subject:
    topic: Major Animal Breeding
  subject:
    topic: Gray
  subject:
    topic: coat color
  subject:
    topic: cattle
  subject:
    topic: Nellore
  subject:
    topic: Angus
  subject:
    topic: genome-wide association
  subject:
    topic: CORIN
  subject:
    topic: PDGFRA
  identifier: http://hdl.handle.net/1969.1/155193
  record info:
    record content source: TXA
    record creation date: 160308
    record change date: 20170928112503.0
    record identifier: in00003610401
    language of cataloging:
      language term: eng