Bisphosphonates in Clinical Oncology : the Development of Pamidronate /

This book provides a clinically oriented overview on the patho-physiological background and the use of bisphosphonates in oncology. The clinical development of pamidronate to treat tumor-induced hypercalcemia and malignant osteolytic bone disease is demonstrated, as well as the results of pivotal st...

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Bibliographic Details
Main Author: Thürlimann, Beat
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 1999.
Series:Recent results in cancer research ; 149.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • From the Contents: Mechanisms of Bone Resorption
  • Mechanisms of Bone Formation
  • Factors Regulating Bone Resorbing Cells and Bone Forming Cells
  • Pharmacological Treatment for Disorders of Bone Remodeling
  • Bisphosphonates
  • Historical Background: From a Detergent to a Registered Drug
  • Tumor Induced Hypercalcemia
  • Malignant Osteolytic Bone Disease
  • Pamidronate
  • Pharmacokinetics of Pamidronate in Patients with Bone Metastases
  • Dose Escalation of Pamidronate for Pain Control in Patients with Malignant Osteolytic Bone Disease
  • Recent Developments
  • Future Directions.