Bisphosphonates in Clinical Oncology : the Development of Pamidronate /

This book provides a clinically oriented overview on the patho-physiological background and the use of bisphosphonates in oncology. The clinical development of pamidronate to treat tumor-induced hypercalcemia and malignant osteolytic bone disease is demonstrated, as well as the results of pivotal st...

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Bibliographic Details
Main Author: Thürlimann, Beat
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 1999.
Series:Recent results in cancer research ; 149.
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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245 1 0 |a Bisphosphonates in Clinical Oncology :  |b the Development of Pamidronate /  |c by Beat Thürlimann. 
264 1 |a Berlin, Heidelberg :  |b Springer Berlin Heidelberg,  |c 1999. 
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490 1 |a Recent results in cancer research,  |x 0080-0015 ;  |v 149 
505 0 |a From the Contents: Mechanisms of Bone Resorption -- Mechanisms of Bone Formation -- Factors Regulating Bone Resorbing Cells and Bone Forming Cells -- Pharmacological Treatment for Disorders of Bone Remodeling -- Bisphosphonates -- Historical Background: From a Detergent to a Registered Drug -- Tumor Induced Hypercalcemia -- Malignant Osteolytic Bone Disease -- Pamidronate -- Pharmacokinetics of Pamidronate in Patients with Bone Metastases -- Dose Escalation of Pamidronate for Pain Control in Patients with Malignant Osteolytic Bone Disease -- Recent Developments -- Future Directions. 
520 |a This book provides a clinically oriented overview on the patho-physiological background and the use of bisphosphonates in oncology. The clinical development of pamidronate to treat tumor-induced hypercalcemia and malignant osteolytic bone disease is demonstrated, as well as the results of pivotal studies. New important findings on how to best use pamidronate in certain indications are given and put in perspective. The author discusses patient management guidelines as well as pharmaco-economic aspects important for the readers. 
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