Cover Image

Biology of Negative Strand RNA Viruses: The Power of Reverse Genetics /

Show other versions (2)

Negative-strand RNA viruses, so named because of the polarity of their genomic RNA to mRNA, include important human and non-human pathogens. Reverse genetics, a technique that allows generation of recombinant viruses, was first developed for negative-strand RNA viruses in 1989. Since then, it has ac...

Full description

Bibliographic Details
Main Author: Kawaoka, Y. (Yoshihiro)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2004.
Series:Current topics in microbiology and immunology ; 283.
Subjects:
Medicine.
Medical virology.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Introduction
  • Reverse Genetics of Monegavirales
  • Reverse systems for the generation of segmented negative-sense RNA viruses entirely from cloned cDNA
  • Transcription and replication of non-segmented negative strand RNA viruses
  • Orthomyxovirus replication, transcription, and polyadenylation
  • Escaping from the cell: Assembly and budding of negative-strand RNA viruses
  • Identification and characterization of viral antagonists of type I interferon in negative-strand RNA viruses
  • Towards multivalent vaccines and therapeutic viruses
  • Influenza vaccines generated by reverse genetics
  • Subject index.