Nongenotoxic Carcinogenesis /

The majority of human chemical carcinogens are capable of damaging DNA and are loosely defined as "genotoxic". On the other hand some chemicals which are described as non-genotoxic appear to increase the incidence of rodent cancers only as a secondary consequence of other induced toxicity....

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Bibliographic Details
Main Author: Cockburn, Andrew
Corporate Author: SpringerLink (Online service)
Other Authors: Smith, Lewis
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 1994.
Series:Ernst Schering Research Foundation workshop ; 10.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:The majority of human chemical carcinogens are capable of damaging DNA and are loosely defined as "genotoxic". On the other hand some chemicals which are described as non-genotoxic appear to increase the incidence of rodent cancers only as a secondary consequence of other induced toxicity. The primary action does not involve DNA damage. This book presents the concept of non-genotoxic carcinogenesis, including possible mechanisms of action. The papers presented by prominent workers provide a detailed insight into the complexity of the field.
Item Description:Electronic resource.
Physical Description:1 online resource (xii, 240 pages)
ISBN:9783662030226 (electronic bk.)
3662030225 (electronic bk.)
ISSN:0947-6075 ;