Neuroinflammation in Stroke /

The successful treatment of acute stroke remains one of the major challenges in clinical medicine. Over the last decades, the understanding of stroke pathophysiology has greatly improved, while the therapeutic options in stroke therapy remain very limited. Today, hyperacute mechanisms of damage, suc...

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Bibliographic Details
Main Author: Dirnagl, U.
Corporate Author: SpringerLink (Online service)
Other Authors: Elger, B.
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2004.
Series:Ernst Schering Research Foundation workshop ; 47.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:The successful treatment of acute stroke remains one of the major challenges in clinical medicine. Over the last decades, the understanding of stroke pathophysiology has greatly improved, while the therapeutic options in stroke therapy remain very limited. Today, hyperacute mechanisms of damage, such as excitotoxicity, can be discriminated from delayed ones, such as inflammation and apoptosis. Targeting of inflammation has already been successfully applied in various stroke models, but translation into a clinically efficacious strategy has not been achieved so far. In this book, leading experts in basic cerebrovascular research as well as stroke treatment review the current evidence for and against an important role for inflammation in stroke, and explore the potential of treating or modulating inflammation in stroke therapy.
Item Description:Electronic resource.
Physical Description:1 online resource (xii, 224 pages)
ISBN:9783662054260 (electronic bk.)
3662054264 (electronic bk.)
ISSN:0947-6075 ;