Non-Myeloablative Allogeneic Transplantation /
Non-myeloablative allogeneic stem cell transplantation (also known as mini-transplantation or reduced-intensity conditioning transplantation) is a major advance in the field of hematopoietic transplantation within the last 5 years. This approach uses non-cytotoxic or reduced-intensity cytotoxic ther...
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| Format: | eBook |
| Language: | English |
| Published: |
Boston, MA :
Springer US,
2002.
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| Series: | Cancer treatment and research ;
110. |
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| Online Access: | Connect to the full text of this electronic book |
| Summary: | Non-myeloablative allogeneic stem cell transplantation (also known as mini-transplantation or reduced-intensity conditioning transplantation) is a major advance in the field of hematopoietic transplantation within the last 5 years. This approach uses non-cytotoxic or reduced-intensity cytotoxic therapy to prepare patients for allografting of hematopoietic stem cells and lymphocytes. It has the potential to deliver the potent anti-tumor immunotherapy and bone marrow replacement capacity of allogeneic stem cell transplantation to patients with reduced treatment-related morbidity and mortality. It may also enable allogeneic transplantation in patients who would be considered ineligible for conventional transplants because of co-morbidity or advanced age. However, this approach may necessitate more careful monitoring of post-transplant chimerism and malignant disease-status than is usual with conventional allografting. There is also controversy regarding the best preparative regimen and graft-versus-host disease prophylaxis to use. |
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| Item Description: | Electronic resource. |
| Physical Description: | 1 online resource (x, 216 pages) |
| ISBN: | 9781461509196 (electronic bk.) 146150919X (electronic bk.) |
| ISSN: | 0927-3042 ; |