The Genetics of Complex Thyroid Diseases /

The autoimmune thyroid diseases and familial thyroid cancers are the current target of molecular thyroid genetics. Unlike the situation in monogenic thyroid diseases, for which the molecular genetics has largely been clarified over the past 20 years, a methodological approach to these more complex f...

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Bibliographic Details
Main Author: Akamizu, T. (Takashi)
Corporate Author: SpringerLink (Online service)
Other Authors: Kasuga, Masato, Davies, Terry F.
Format: eBook
Language:English
Published: Tokyo : Springer Japan, 2002.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Part 1. Autoimmune Thyroid Diseases: Genetic dissection of familial autoimmune thyroid diseases using whole genome screening
  • Genome screening for Graves' disease susceptibility Loci in U.K. families
  • The involvement of the HLA region in genetic susceptibility to Graves' disease
  • HLA and Autoimmune Thyroid Diseases
  • What can we learn from the genetics of diabetes?- The Genomic Biology of the Human Chromosome 2q33 Costimulatory Receptor Region
  • CTLA-4 gene in the pathogenesis of Graves' disease
  • The evolving role of CTLA-4 in the genetic predisposition to AITD
  • Association of AITD with microsatellite markers for TSHR and CTLA-4 in Japanese patients
  • Part 2. Familial Thyroid Cancers: Familial non medullary thyroid cancer
  • Cowden's disease and the Pten/Mmac1 Gene
  • Molecular mechanisms of RET activation in human neoplasia
  • Lesson from Chernobyl; need for molecular epidemiology of childhood thyroid cancer
  • Genetic events in radiation-induced thyroid cancer.