Computer Simulations of Protein Structures and Interactions /
Lecture Notes in Chemistry Protein engineering endeavors to design new peptides and proteins or to change the structural and/or functional characteristics of existing ones for specific purposes, opening the way for the development of new drugs, vaccines, and industrial enzymes. Computer assisted sim...
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg,
1995.
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| Series: | Lecture notes in chemistry ;
66. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | Lecture Notes in Chemistry Protein engineering endeavors to design new peptides and proteins or to change the structural and/or functional characteristics of existing ones for specific purposes, opening the way for the development of new drugs, vaccines, and industrial enzymes. Computer assisted simulations play an important role, as an auxiliary tool, in this task. This work develops in a comprehensive way the theoretical formulation for the methods used in computer-assisted modeling and predictions, starting from the basic concepts and proceeding to the more sophisticated methods, such as Monte Carlo and molecular dynamics. An evaluation of the approximations inherent to the simulations will allow the reader to obtain a perspective of the possible deficiencies and difficulties and approach the task with realistic expectations. Examples from the authors laboratories, as well as from the literature provide useful information. |
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| Item Description: | Electronic resource. |
| Physical Description: | 1 online resource (xii, 284 pages) |
| ISBN: | 9783642514999 (electronic bk.) 3642514995 (electronic bk.) |
| ISSN: | 0342-4901 ; |