Data Mining in Structural Biology : Signal Transduction and Beyond /
This book combines in a comprehensive manner the results of biochemical studies, structural biology investigations and small molecule design within some of the protein classes that play major roles in signal transduction: the protein kinases, the growth factor family and the transcription factors. I...
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| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg,
2001.
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| Series: | Ernst Schering Research Foundation workshop ;
34. |
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| Online Access: | Connect to the full text of this electronic book |
| Summary: | This book combines in a comprehensive manner the results of biochemical studies, structural biology investigations and small molecule design within some of the protein classes that play major roles in signal transduction: the protein kinases, the growth factor family and the transcription factors. It is described how these proteins communicate with each other via different signalling pathways. Three-dimensional structures of these proteins are presented, and their interaction with small molecules and co-factors are described. The use of these proteins for pharmaceutical research and the design of small molecules and their selectivity towards such proteins are discussed. |
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| Item Description: | Electronic resource. |
| Physical Description: | 1 online resource (xiii, 209 pages) |
| ISBN: | 9783662046456 (electronic bk.) 3662046458 (electronic bk.) |
| ISSN: | 0947-6075 ; |