http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
This volume intends to provide a panorama of our current understanding of the role of genetic information in the management of cardiovascular disease. A recurring plea from the contributors is the need for more hypothesis-driven, rigorously conducted and analysed clinical research. Perhaps this compilation of knowledge will provide a springboard for the design of informative clinical studies.
Preface -- The Role of Genotyping in Pharmacological Therapy -- Pharmacogenetics and the Treatment of Cardiovascular Disease -- Genetic Polymorphisms and Cardiovascular Drug Metabolism -- Genes that Modify Susceptibility to Atherosclerosis: Targets for Drug Action -- Lipid Lowering Responses Modified by Genetic Variation -- The Genetic Basis of Essential Hypertension and its Implications for Treatment -- Genetic Predisposition to Cardiac Hypertrophy -- Genetic Determinants of Susceptibility, Prognosis and Treatment in Heart Failure -- The Genetics of Cardiac Channelopathies: Implications for Therapeutics -- Insulin Resistance and Cardiovascular Disease -- New Insights From Genetics -- Genetic Disruption of Nitric Oxide Synthases and Cardiovascular Disease -- Lessons from a Candidate Gene -- Association of Thrombotic Disease with Genetic Polymorphism of Haemostatic Genes -- Relevance to Pharmacogenetics -- Genetic Polymorphisms of Adhesion Molecules -- Genetic Regulation of Metalloproteinase Activity: Pathogenic and Therapeutic Implications -- Current Perspectives on Gene and Cell-based Therapies for Myocardial Protection, Rescue and Repair.
Includes bibliographical references and index.
Handbook of experimental pharmacology ; 160