Host Defense Dysfunction in Trauma, Shock and Sepsis : Mechanisms and Therapeutic Approaches /

This book contains a unique overview of the sequence of steps of host defense impairment that result from injury and lead to multiple organ dysfunction syndrome. The crucial alterations of immune and inflammatory mechanisms as they are seen during ischemia, during inter- mediate inflammatory phases,...

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Bibliographic Details
Main Author: Faist, E. (Eugen)
Corporate Author: SpringerLink (Online service)
Other Authors: Meakins, Jonathan L., Schildberg, F. W. (Friedrich W.)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 1993.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • General Aspects/Perspectives
  • Host defense integrity, response and stress
  • From injury to multiple organ failure: Sequential steps of host defense impairment
  • Immune mechanisms for the control of infection under physiologic and stressful conditions
  • Inflammatory mechanisms in traumatic and septic injury
  • Hepatocellular injury in ischemia, trauma and sepsis
  • Cytokines and modulation of cytokine action
  • Cytokines in acute phase states and trauma
  • The mediator role of TNF in sepsis
  • Endotoxin
  • mechanisms of actions and protection from shock
  • Clinical aspects of multiple organ failure
  • The pathophysiologic impact of bacterial translocation and strategies for its prevention
  • Antibiotic interactions with host defenses
  • The role of nutrition in host defense
  • New insight into the mechanisms of wound healing
  • Therapeutic immunomodulatory approaches: Prevention
  • Endotoxin neutralization with IV-immunogloblins and monclonal anti-endotoxin antibodies
  • Interventional strategies in the therapy of septic shock.-