rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Continuous Dopaminergic Stimulation in Parkinson's Disease
    sub title: Proceedings of the Workshop in Alicante, Spain, September 22-24, 1986
  name:
    name part: Obeso, J. A.
    role:
      role term: creator
  name:
    name part: Horowski, R.
  name:
    name part: Marsden, C. D.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  genre: Electronic books.
  origin info:
    place:
      place term: au
    date issued: 1988
    issuance: monographic
  language:
    language term: eng
  physical description:
    reformatting quality: access
    form: remote
    extent: 1 online resource (xii, 255 pages 58 illustrations)
  abstract: At this meeting, a number of critical groups confirmed and extended the original findings by J.A. Obeso and his colleagues. These authors found that continuous s.c. infusion of lisuride, a watersoluble dopaminergic 8- -aminoergoline with dopaminergic properties which can be injected or infused, can improve - sometimes quite considerably - motor function in severely disabled fluctuating Parkinsonian patients. The concurrent use of the peripheral dopamine antagonist domperidone attenuates or prevents side effects related to the stimulation of "peripheral" dopamine receptors, including the chemoreceptor trigger zone and some areas of the hypothalamus outside the blood-brain barrier. The clinical results discussed in this volume may not only be a basis for further improvements in our knowledge and therapeutic strategies in Parkinsonism, they point to the so far neglected importance of different ways of stimulating neurological or other systems, e.g. discontinous, oscillatory effects caused by frequent oral application vs. continuous stimulation as described here with the lisuride s.c. infusion. Similar concepts have to be discussed and investigated in neurological disorders. In this respect, this multidisciplinary meeting and its publication may offer new ideas and concepts for therapy in general, in addition to its potential application in the treatment of the complications of Parkinson's disease.
  table of contents: Continuous Dopaminergic Stimulation in Parkinson's Disease -- Complications in Treatment -- Continuous Dopaminergic Stimulation Experimental Studies -- Biochemical Basis of Diagnostic and Therapeutic Problems -- Present State and Future Developments.
  note: edited by J.A. Obeso, R. Horowski, C.D. Marsden.
  note: Electronic resource.
  subject:
    topic: Medicine
  subject:
    topic: Neurosciences
  subject:
    topic: Toxicology
  subject:
    topic: Neurology
  subject:
    topic: Psychiatry
  subject:
    topic: Medicine
  subject:
    topic: Neurology
  subject:
    topic: Neurosciences
  subject:
    topic: Psychiatry
  subject:
    topic: Toxicology
  classification: RC346-429.2
  classification: 616.8
  related item:
    title info:
      title: Journal of Neural Transmission ; 27
  identifier: 9783709189542 (electronic bk.)
  identifier: 3709189543 (electronic bk.)
  identifier: 9783211820346
  identifier: 3211820345
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: AU@
    record creation date: 120123
    record change date: 20260422202145.3
    record identifier: in00003566933
    language of cataloging:
      language term: eng