Phosphoinositides in Subcellular Targeting and Enzyme Activation /

The reversible recruitment of intracellular protein complexes to membranes is essential for immune cell functions, including chemotaxis, phagocytosis and signalling. Such recruitment is often controlled by phosphorylated derivatives of phosphatidylinositol, known as phosphoinositides. These lipids a...

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Bibliographic Details
Main Author: Stenmark, H. (Harald)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2004.
Series:Current topics in microbiology and immunology ; 282.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Preface
  • Phosphoinositide involvement in phagocytosis and phagosome maturation
  • Regulation of endocytosis by phosphatidylinositol 4,5-biphosphate and ENTH proteins
  • Membrane targeting by pleckstrin homology (PH) domains
  • Protein targeting to endosomes and phagosomes via FYVE and PX domains
  • Regulation of the actin cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3
  • Roles of PI3K in neutrophil function
  • Nuclear phosphoinositides and their functions
  • Subject index.