Phosphoinositides in Subcellular Targeting and Enzyme Activation /
The reversible recruitment of intracellular protein complexes to membranes is essential for immune cell functions, including chemotaxis, phagocytosis and signalling. Such recruitment is often controlled by phosphorylated derivatives of phosphatidylinositol, known as phosphoinositides. These lipids a...
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| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg,
2004.
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| Series: | Current topics in microbiology and immunology ;
282. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | The reversible recruitment of intracellular protein complexes to membranes is essential for immune cell functions, including chemotaxis, phagocytosis and signalling. Such recruitment is often controlled by phosphorylated derivatives of phosphatidylinositol, known as phosphoinositides. These lipids also serve to activate enzyme systems that carry out complex reactions such as chromatin remodelling and pre-mRNA procesing. This issue of Current Topics in Microbiology and Immunology presents an overview of how phosphoinositides function in protein recruitment and enzyme activation and presents physiologically important examples of protein-phosphoinositide interactions. |
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| Item Description: | Electronic resource. |
| Physical Description: | 1 online resource (xi, 209 pages) |
| ISBN: | 9783642188053 (electronic bk.) 3642188052 (electronic bk.) |
| ISSN: | 0070-217X ; |