Lentiviral Vectors /

For the first time a compilation of chapters that depict the biological basis underlying the development of lentiviral vectors, the techniques involved in the manufacture of this new gene delivery tool, and its most promising applications.

Bibliographic Details
Main Author: Trono, Didier
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2002.
Series:Current topics in microbiology and immunology ; 261.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Introduction
  • Molecular biology of lentivirus-mediated gene transfer
  • HIV-derived lentiviral vectors
  • SIV-derived lentiviral vectors
  • Non-primate lentiviral vectors
  • Production of lentiviral vectors
  • Biosafety issues in lentiviral vector production
  • Lentiviral vector targeting
  • Integration site selection by lentiviruses: biology and possible control
  • Improving the posttranscriptional aspects of lentiviral vectors
  • Lentiviruses as vectors for CNS diseases
  • Lentiviral vectors for the gene therapy of lympho-hematological disorders
  • Lentiviral vectors for gene therapy of HIV-induced disease
  • Opportunities for the use of lentiviral vectors in human gene therapy
  • Subject index.