The Small GTPase Ran /

The Ras-related nuclear protein Ran is a member of the so-called Ras-superfamily of small GTP-binding proteins and hydrolyzing proteins. A variety of edited anthologies related to the Ras-superfamily have appeared over the last decade, but Ran has been under-represented in all of them. This under-re...

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Bibliographic Details
Main Author: Rush, Mark
Corporate Author: SpringerLink (Online service)
Other Authors: D'Eustachio, Peter
Format: eBook
Language:English
Published: Boston, MA : Springer US : Imprint : Springer, 2001.
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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520 |a The Ras-related nuclear protein Ran is a member of the so-called Ras-superfamily of small GTP-binding proteins and hydrolyzing proteins. A variety of edited anthologies related to the Ras-superfamily have appeared over the last decade, but Ran has been under-represented in all of them. This under-representation is not due to the fact that Ran is unimportant or non-abundant. It is almost certainly because Ran was discovered and its functions elucidated only recently, and that some of these functions may not follow the typical Ras-superfamily paradign.<br/> Even workers in the field have difficulty keeping up with the Ran literature, and most outsiders rarely try even though they may be aware that major breakthroughs regarding the mechanisms of nuclear-cytosolic transport, mitosis and the maintenance of nuclear structure have depended upon an understanding of Ran function. <em>The</em> <em>Small GTPase Ran</em> is meant to provide specialists with a concise summary of some of the recent research in this area, along with background describing its initial identification and early characterization. 
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