Immunobiology of Bacterial CpG-DNA /
Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules...
| Main Author: | |
|---|---|
| Corporate Author: | |
| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg,
2000.
|
| Series: | Current topics in microbiology and immunology ;
247. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Mechanism of Action of CpG DNA
- Oligodeoxyribonucleotides with 5'-ACGT-3' or 5'-TCGA-3' Sequence Induced Production of Interferons
- Macrophage Activation by Immunostimulatory DNA
- Consequences of Bacterial CpG DNA-Driven Activation of Antigen-Presenting Cells
- Signal Transduction Pathways Activated by CpG-DNA
- CpG DNA Co-Stimulated Antigen-Reactive T Cells
- Role of Type I Interferons in T Cell Activation Induced by CpG DNA
- Hematopoietic Remodelling Triggered by CpG DNA
- CpG DNA Augments the Immunogenicity of Plasmid DNA Vaccines
- The Role of Bacterial DNA in Autoantibody Induction
- CpG DNA in Cancer Immunotherapy
- Use of CpG DNA for Enhancing Specific Immune Responses
- Immunostimulatory-Sequence DNA is an Effective Mucosal Adjuvant
- CpG DNA Switches on Th1 Immunity and Modulates Antigen-Presenting Cell Function
- Effects of CpG DNA on Th1/Th2 Balance in Asthma
- Responses of Human B Cells to DNA and Phosphorothiase Oligodeoxynucleotides.