Immunobiology of Bacterial CpG-DNA /
Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules...
| Main Author: | |
|---|---|
| Corporate Author: | |
| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg,
2000.
|
| Series: | Current topics in microbiology and immunology ;
247. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field. |
|---|---|
| Item Description: | Electronic resource. |
| Physical Description: | 1 online resource (IX, 246 pages 34 illustrations) |
| ISBN: | 9783642596728 (electronic bk.) 364259672X (electronic bk.) |