http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
elucidating basic cellular mechanisms for future therapeutic discovery
1 online resource (xiv, 305 pages) : illustrations
Understanding the crucial link between basic science discovery and the development of therapeutic regimens for clinical disease offers the greatest potential to either prevent or reverse central nervous system disability. Neuronal and Vascular Plasticity: Elucidating Basic Cellular Mechanisms for Future Therapeutic Discovery addresses novel repair mechanisms for cellular injury and integrates current knowledge of basic disease mechanisms of the brain with clinical approaches. This volume is intended to serve as a strong reference for those entering the clinical neurosciences as well as for those established in the field.
Transformation into treatment: novel therapeutics that begin within the cell -- Cholinergic plasticity and the meaning of death -- Restorative potential of angiogenesis after ischemic stroke -- Vascular endothelial function: role of gonadal steroids -- Alterations of synaptic transmission following transient cerebral ischemia -- The future of brain protection: natural alternatives -- Iron's involvement in the molecular mechanisms and pathogenesis of Alzheimer's disease -- Ethanol-induced neurodegradation: basic mechanisms and therapeutic approaches -- Regulation of neural stem cells in the adult mammalian brain -- G-protein mediated metabotropic receptors offer novel avenues in neuronal and vascular cells for cytoprotective strategies.
edited by Kenneth Maiese, Professor of Neurology and Anatomy & Cell Biology, Director, Division of Cellular and Molecular Cerebral Ischemia, Center for Molecular Medicine, Institute for Environmental Health Sciences, Wayne State University School of Medicine, Detroit, MI.
Includes bibliographical references and index.