Protein Degradation in Health and Disease /

Protein degradation has been identified as a centerpiece of regulation of cell functions. Not surprisingly, its deregulation is implied in almost any pathological condition. This book describes how aged proteins are eliminated during cell metabolism, how cell proliferation is regulated by protein de...

Full description

Bibliographic Details
Main Author: Reboud-Ravaux, Michèle
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint : Springer, 2002.
Series:Progress in molecular and subcellular biology ; 29.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Roles of SCF and VHL Ubiquitin Ligases in Regulation of Cell Growth
  • Aging of Proteins and the Proteasome
  • Pathways of Protein Degradation and How They Are Affected by Age
  • Protein Degradation in Alzheimer's Disease and Aging of the Brain
  • Protein Degradation in Human Disease
  • The 26S Proteasome
  • Proteasome Inhibitors.