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Mechanisms and mediators of neuropathic pain /

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Numerous improvements in our understanding of the mechanisms that underlie neuropathic pain states have come from the development of animal models, most of which involve partial peripheral nerve injury. The animal models have shown that nerve injury initiates a cascade of events resulting in altered...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Malmberg, Annika B., 1966-, Chaplan, Sandra R.
Format: eBook
Language:English
Published: Basel ; Boston : Birkhäuser Verlag, [2002]
Series:PIR (Series)
Subjects:
Neuralgia > Pathophysiology.
Neuralgia > Molecular aspects.
Neuralgia.
Hyperalgesia.
Peripheral Nerve Injuries.
Spinal Cord > physiopathology.
Trauma, Nervous System > physiopathology.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • From the contents: Electrophysiological characteristics of injured peripheral nerves
  • Sodium channels and the molecular basis for pain
  • Changes in DRG neurons after nerve injury: possible involvement in the development and maintenance of neuropathic pain
  • Neuroinflammation, cytokines and neuropathic pain
  • Pharmacological plasticity associated with neuropathic pain states
  • Sprouting and reorganization in the spinal cord after nerve injury
  • Animal models of toxic and metabolic sensory neuopathies
  • Role of adrenergic transmitters and receptors in nerve and tissue injury related pain
  • Evaluation of neuropathic pain
  • Glutamate receptor antagonists and neuropathic pain.