Transgenic Models in Pharmacology /

The aim of this volume is to give up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilita...

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Bibliographic Details
Main Author: Offermanns, Stefan
Corporate Author: SpringerLink (Online service)
Other Authors: Hein, Lutz
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint : Springer, 2004.
Series:Handbook of experimental pharmacology ; 159.
Subjects:
Online Access:Connect to the full text of this electronic book

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245 1 0 |a Transgenic Models in Pharmacology /  |c edited by Stefan Offermanns, Lutz Hein. 
246 3 |a With contributions by numerous experts 
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490 1 |a Handbook of Experimental Pharmacology, 0171-2004 ;  |v 159 
504 |a Includes bibliographical references and index. 
505 0 |a From the Contents: Preface -- I: Transgenic Techniques -- II: Molecular Systems -- III: Nervous System -- IV: Cardiovascular System -- V: Immunology/Hematology/Inflammation -- VI: Endocrinology -- VII: Toxicology. 
520 |a The aim of this volume is to give up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important genetically engineered animal models and their phenotypes. This book aims at illustrating the impact of transgenic animal models in the field of Experimental Pharmacology and Toxicology, which includes their role in the understanding of basic cellular mechanisms, the evaluation of potential drug targets or the testing for drug effects. 
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