Cancer -- Between Glycolysis and Physical Constraint /
Considerable effort has gone into the research of common cancers - lung, bowel, ovarian, cervical, and prostate cancer. In recent years, however, there has been a lack of breakthroughs in therapeutic advances. By challenging many established beliefs, Cancer explores these issues by offering new pers...
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| Format: | eBook |
| Language: | English |
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Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint : Springer,
2004.
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| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Introduction
- Are Cancer Cells Malignant Per Se?- Cell Growth: a Balance Between Glycolysis and Physical Constraint
- Extracellular Constraints Regulate Cell Differentiation
- Changes in Cellular Constraints During Carcinogenesis
- Hypoxia is Responsible for Changes in Cellular Constraints During Inflammation
- Fibrosis Perpetuates Hypoxia
- Metastasis: the Hunt for Food
- Carcinogens Target Cell Respiration and Induce Glycolysis
- Epidemiology: Aging as the Main Cause of Cancer
- Aging Causes Inflammation and Fibrosis Mimicking the Impact of Carcinogens
- Inhibition of Metabolism Slows Aging and Decreases Cancer Incidence
- A Complication of Hypoxia: the Loss of Cell Polarity Explains Cancer Cell Proliferation
- The Loss of Cell Differentiation is a Consequence of Glycolysis
- Response to Treatment: a Balance Between Glycolysis and Physical Constraints
- Targeting Glycolysis
- Conclusion.