Cholesterol : its functions and metabolism in biology and medicine /

Experts investigate the biochemical and biomedical aspects of cholesterol, addressing its metabolism in normal and disease states. They discuss a broad range of topics, including key steps in the cholesterol biosynthetic pathway, and the role of cholesterol in cancer, atherosclerosis, and diseases o...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Bittman, Robert
Format: eBook
Language:English
Published: New York : Plenum Press, [1997]
Series:Sub-cellular biochemistry ; v. 28.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Signaling molecules derived from the cholesterol biosynthetic pathway
  • Coordinate regulation of cholesterol 7a-hydroxylase and HMG-CoA reductase in the liver
  • Polyprenyl diphosphate synthases
  • Antifungal sterol biosynthesis inhibitors
  • The Smith-Lemli-Opitz syndrome: a potentially fatal birth defect caused by a block in the last enzymatic step in cholesterol biosynthesis
  • Has nature designed the cholesterol side chain for optimal interaction with phospholipids?
  • Cholesterol and myelin
  • Regulation of mitochondrial cholesterol metabolism
  • Lipoproteins and cellular cholesterol homeostasis
  • Cholesterol-sphingomyelin interactions in cells - effects on lipid metabolism
  • Mechanisms and (patho)physiological significance of biliary cholesterol secretion
  • Cholesterol deposition in atherosclerotic lesions
  • Cholesterol metabolism and tumor cell proliferation
  • Biological implications of the Niemann-Pick C mutation
  • Sitosterolemia
  • Cholesterol cytochemistry in cell biology and disease
  • Approaches for the design of novel anti-atherogenic compounds
  • Index.