Peptide Transport and Delivery into the Central Nervous System /

Hypo- or hypersecretion, alteration in storage, release, catabolism, and post-translational processing of neuropeptides are associated with the etiology of many diseases affecting the central nervous system (CNS). Various peptides native to the brain and the spinal cord, as well as various synthetic...

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Bibliographic Details
Main Author: Prokai, Laszlo
Corporate Author: SpringerLink (Online service)
Other Authors: Prokai-Tatrai, Katalin
Format: eBook
Language:English
Published: Basel : Birkhäuser Basel : Imprint : Birkhäuser, 2003.
Series:Progress in drug research ; 61.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Fleur L. Strand: Neuropeptides: general characteristics and neuropharmaceutical potential in treating CNS disorders
  • David J. Begley and Milton W. Brightman: Structural and functional aspects of the blood-brain barrier
  • Abba J. Kastin and Weihong Pan: Peptide transport across the blood-brain barrier
  • Intracranial delivery of proteins and peptides as a therapy for neurodegenerative diseases
  • David Fortin: Altering the properties of the blood-brain barrier: disruption and permeabilization
  • Katalin Prokai-Tatrai and Laszlo Prokai: Modifying peptide properties by prodrug design for enhanced transport into the CNS
  • Suresh P. Vyas: CNS-delivery via conjugation to biological carriers: physiological-based approaches
  • Jamal Temsamani and Jean-Michel Scherrmann: Peptide vectors as drug carriers. Index Vol. 61.