Calcium Channel Blockers /

The main effect of calcium channel blockers is the blockade of calcium entry into cells through voltage operated calcium channels. This volume gives a comprehensive overview of the different classes of CCBs and their various effects. It covers historical development, pharmacology, clinical aspects,...

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Bibliographic Details
Main Author: Godfraind, T. (Théophile)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Basel : Birkhäuser Basel : Imprint : Birkhäuser, 2004.
Series:Milestones in drug therapy.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Preface
  • Acknowledgements
  • Historical perspective: from early steps on calcium research to the identification of calcium antagonist prototypes and of the signaling functions of Ca2+
  • Calcium channel blockers and calcium channels
  • The action of calcium antagonists on Ca2+ movements in isolated vessels
  • The tissue selectivity of calcium antagonists
  • Acute haemodynamic effects of calcium channel blockers
  • Calcium channels and regulation of vascular tone in hypertension
  • Long-term effects of calcium antagonists
  • Blood-pressure independent effects of calcium antagonists
  • From early clinical studies to randomized controlled clinical trials
  • Beyond the cardiovascular system
  • Index.