Clostridial neurotoxins : the molecular pathogenesis of tetanus and botulism /
This book describes all biological and biomedical aspects of the action of neurotoxins responsible for the neuroparalytic syndromes of tetanus and botulism. Recently, new fundamental information on the molecular mechanism of action of these neurotoxins has emerged. In particular, clostridial neuroto...
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| Format: | eBook |
| Language: | English |
| Published: |
Berlin ; New York :
Springer,
[1995]
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| Series: | Current topics in microbiology and immunology ;
195. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | This book describes all biological and biomedical aspects of the action of neurotoxins responsible for the neuroparalytic syndromes of tetanus and botulism. Recently, new fundamental information on the molecular mechanism of action of these neurotoxins has emerged. In particular, clostridial neurotoxins were found to be a new group of zinc- endopeptidases blocking exocytosis by the very specific cleavage of three protein components of the exocytosis apparatus. This property is described in detail in the book together with other information that will enable the reader to appropriately use these toxins in the study of cell processes involving their three protein targets. These toxins are already used and will be increasingly used in the future as powerful tools in cell biology and neurosciences. |
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| Physical Description: | 1 online resource (vii, 278 pages) : illustrations. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9783642851735 (electronic bk.) 3642851738 (electronic bk.) |