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Applied statistics in the pharmaceutical industry : with case studies using S-Plus /

The purpose of this book is to provide a general guide to statistical methods used in the pharmaceutical industry, and to illustrate how to use S-PLUS to implement these methods. Specifically, the goal is to: *Illustrate statistical applications in the pharmaceutical industry; *Illustrate how the st...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Millard, Steven P., Krause, Andreas
Format: eBook
Language:English
Published: New York : Springer, [2001]
Subjects:
Drugs > Research > Statistical methods.
Médicaments > Recherche > Méthodes statistiques.
Drug Industry > methods.
Statistics as Topic > methods.
Mathematical Computing.
Software.
Arzneimittelentwicklung.
Medizinische Statistik.
S-PLUS.
Pharmacie > Recherche > Méthodes statistiques.
S-Plus (logiciel)
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Introduction
  • Analysis of Large Designed Experiments Using Trellis Graphics and Tree-Based Regression
  • Using S-PLUS to Perform Sample Size Calculations
  • Design and Analysis of Two-Period Cross-Over Trials
  • Analysis of Pharmacokinetic Studies
  • Patient Compliance and Its Impact on Steady State Pharmacokinetics
  • Survival Analysis to Compare Two Treatments in a Large Phase III Trial
  • Using S-PLUS and SAS for ANOVA and Contrasts
  • Using S-PLUS to Construct Design-Based Permutation Tests for a Variety of Endpoints and Designs in Phase III Clinical Trials
  • Graphical Presentation of Single Patient Results
  • Using The Seattle Angine Questionnaire as a Primary Outcome in Clinical Trials
  • Health Economics
  • Statistical Methodology and S- PLUS Programming for the Evaluation of the Decimal Reduction Time of a Sterilization Process in Pharmaceutical Production
  • Acceptance Sampling Using S-PLUS.