Neurobiological mechanisms of opiate withdrawal /

Some general aspects of opiate dependence are described in a first section including a brief historical description and an explanation of the different models currently used to investigate opiate dependence. The neurobiological bases of opiate withdrawal are detailed in a second section, which parti...

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Bibliographic Details
Main Author: Maldonado, Rafael, 1961-
Corporate Author: SpringerLink (Online service)
Other Authors: Stinus, Luis, Koob, George F.
Format: eBook
Language:English
Published: New York : Springer : R.G. Landes, [1996]
Series:Neuroscience intelligence unit (Unnumbered)
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:Some general aspects of opiate dependence are described in a first section including a brief historical description and an explanation of the different models currently used to investigate opiate dependence. The neurobiological bases of opiate withdrawal are detailed in a second section, which particularly emphasizes the neurophysiological adaptative changes, the processes of homologous and heterologous regulation, and the role played by different brain structures and several endogenous peptides acting as antiopiates. The last part reports several basic aspects more directly related to the clinical perspectives of opiate dependence, such as the new expectations in the treatment of opiate withdrawal or the relationships between sensitization, tolerance and withdrawal.
Physical Description:1 online resource (204 pages) : illustrations.
Bibliography:Includes bibliographical references and index.
ISBN:9783662222188 (electronic bk.)
3662222183 (electronic bk.)