Neurodegenerative disorders : through gain of function /

A fundamental change is occurring in the understanding of the major neurodegenerative disorders. Protein aggregation is a common emerging theme in diseases as diverse as Alzheimer's, Creutzfeld-Jakob, Parkinson's, and amyotrophic lateral sclerosis. If valid, then a small number of diagnost...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Beyreuther, K. (Konrad), 1941-, Christen, Yves, Masters, Colin L.
Format: eBook
Language:English
Published: Berlin : Springer, 2001.
Series:Research and perspectives in Alzheimer's disease.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • From the contents: The natural history of Alzheimer's Disease: minding the gaps in understanding the mechanisms of neurodegeneration
  • Pathological mechanisms in Huntingdon's Disease and other polyglutamine expansion diseases
  • Prion protein biogenesis: implications for neurodegeneration
  • The value of transgenic models for the study of neurodegenerative diseases
  • Pathogenesis and mechanisms of cerebral amyloidosis in APP transgenic mice
  • The next step in Notch processing and its relevance to amyloid precursor protein
  • The putative role of presenilins in the transmembrance domain cleavage of amyloid precursor protein and other integral membrane proteins
  • ApoE receptor in the brain: novel signaling pathways with potential relevance for Alzheimer's Disease
  • Homeoprotein intercellular transport: mechanisms, significance and applications
  • And other contributions.