Pathology of Septic Shock /

This volume summarizes the present basic and clinical knowledge on the complex syndrome "sepsis". The current findings rest on an interdisciplinary approach in attempting to unravel the molecular pathways causing this disease. The immune system senses bacterial toxins and is target as well...

Full description

Bibliographic Details
Main Author: Rietschel, E. T.
Corporate Author: SpringerLink (Online service)
Other Authors: Wagner, Hermann
Format: eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 1996.
Series:Current topics in microbiology and immunology ; 216.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:This volume summarizes the present basic and clinical knowledge on the complex syndrome "sepsis". The current findings rest on an interdisciplinary approach in attempting to unravel the molecular pathways causing this disease. The immune system senses bacterial toxins and is target as well. Recent insights into the cellular and molecular mechanisms underlying these processes unravelled for LPS the signal pathways triggering activation and acute cytokine release of the respective target cells. Based on the findings in animal model systems there is an urgend need to evaluate whether in humans the respective state of sensitisation can be defined and influences the impact of bacterial transition in causing the septic syndrome.
Item Description:Electronic resource.
Physical Description:1 online resource (x, 321 pages 34 illustrations)
ISBN:9783642801860 (electronic bk.)
3642801862 (electronic bk.)