Manual of Antisense Methodology /
In the past few years, antisense methodology has moved from <em>in vitro</em> studies to <em>in vivo</em> studies and first human trials. While the basic concept of antisense technology is simple, the methodological problems associated with its use are numerous and complex. A...
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| Format: | eBook |
| Language: | English |
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Boston, MA :
Springer US : Imprint : Springer,
1999.
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| Series: | Perspectives in antisense science ;
4. |
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| Online Access: | Connect to the full text of this electronic book |
| Summary: | In the past few years, antisense methodology has moved from <em>in vitro</em> studies to <em>in vivo</em> studies and first human trials. While the basic concept of antisense technology is simple, the methodological problems associated with its use are numerous and complex. Antisense- based methods have proven to be a field of research where careful attention to experimental protocols and appropriate controls is necessary. <br/> The <em>Manual of Antisense Methodology</em> emphasizes the application of antisense oligonucleotides, and is a guide for the identification of antisense and non-antisense effects in different experimental settings. The work is organized into three sections: antisense application <em>in vitro</em>, antisense application <em>in vivo</em> (animal models) and finally, clinical antisense studies. Where at all possible, the methods are described in sufficient detail to allow reproduction of a given experiment. <br/> The <em>Manual of Antisense Methodology</em> will be of interest to researchers in immunology, cancer research, pharmacology and internal medicine; and physicians conducting clinical studies in these fields. |
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| Item Description: | Electronic resource. |
| Physical Description: | 1 online resource (224 pages) |
| ISBN: | 9781461550679 (electronic bk.) 146155067X (electronic bk.) |