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Estrogens, progestins, and their antagonists
1 online resource (xx, 234 pages) : illustrations (some color ).
I. Estrogen and progestin physiological function. 1. Pituitary and brain actions of estrogen and progesterone in the regulation of primate prolactin secretion ; 2. Saccharomyces cerevisiae as a model system to study steroid hormone receptors ; 3. Physiological findings from transgenic mouse models with altered levels of estrogen receptor expression -- II. Molecular biology of steroid receptors and gene expression. 4. New models and insights in steroid hormone action ; 5. A role for progesterone in multidrug resistance ; 6. Dominant negative activity by estrogen and progesterone receptors ; 7. Estrogen and progesterone receptors in human endometrial cancer -- III. Factors enhancing receptor function. 8. Facilitated binding of steroid hormone receptors to target DNA by the chromatin high-mobility group protein-1: protein manipulation of DNA structure ; 9. Use of FK506 and its analogs in studying progesterone signaling -- Keyword index.
Originally published: Boston : Birkhäuser, 1997.
Includes bibliographical references and indexes.