MAO--the mother of all amine oxidases /

Monoamine oxidase (MAO) is linked to psychiatric and neurological disorders, because inhibitors of the enzyme are used clinically for treatment of affective disorders and Parkinsons disease. One of the interesting new aspects of MAO is the occurrence in the human population of deletions of genes cod...

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Bibliographic Details
Corporate Authors: International Amine Oxidases Workshop Shavei Zion, Israel, SpringerLink (Online service), Rappaport Symposium
Other Authors: Da Prada, M. (honouree.), Finberg, J. P. M. (Editor)
Format: Conference Proceeding eBook
Language:English
Published: Wien ; New York : Springer-Verlag, [1998]
Series:Journal of neural transmission. Supplementum ; 52.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:Monoamine oxidase (MAO) is linked to psychiatric and neurological disorders, because inhibitors of the enzyme are used clinically for treatment of affective disorders and Parkinsons disease. One of the interesting new aspects of MAO is the occurrence in the human population of deletions of genes coding for one or the other enzyme subtype (A or B). This leads to the possibility of a genetic basis for psychiatric disorders based on MAO. Subjects with deletions of type A or B, and combined deletions, have been described. In the first group of 6 papers in this book, the occurrence and characterization of these phenotypes, as well as the structure of MAO genes, is explored. Advances in the biochemistry of MAO subtypes and their physiological function and localization in brain and periphery is included. Other sections of the book deal with the neuroprotective action of MAO inhibitors and their pharmacology, especially the pharmacology of new MAO-B inhibitors.
Item Description:The 6th Rappaport Symposium and 7th International Amine Oxidases Workshop, held in June 1996 at Shavei Zion, Israel, and dedicated to the memory of Dr. Moise Da Prada. Cf. Pref.
Physical Description:1 online resource (xix, 363 pages) : illustrations (some color), portrait.
Bibliography:Includes bibliographical references.
ISBN:9783709164990 (electronic bk.)
3709164990 (electronic bk.)
ISSN:0303-6995 ;