Probabilistic graphical models for genetics, genomics, and postgenomics /

Bibliographic Details
Other Authors: Sinoquet, Christine (Editor), Mourad, Raphaƫl (Editor)
Format: Book
Language:English
Published: Oxford ; New York : Oxford University Press, 2014.
Edition:First edition.
Subjects:
Table of Contents:
  • Pt. I. Introduction
  • Probabilistic graphical models for next-generation genomics and genetics
  • Essentials for probabilistic graphical models : a tutorial about inference and learning
  • pt. II. Gene expression
  • Graphical models and multivariate analysis of microarray data
  • Comparison of mixture Bayesian and mixture regression approaches to infer gene networks
  • Network inference in breast cancer with Gaussian graphical models and extensions
  • pt. III. Causality discovery
  • Utilizing genotypic information as a prior for learning gene networks
  • Bayesian causal phenotype network incorporating genetic variation and biological knowledge
  • Structural equation models for studying causal phenotype networks in quantitative genetics
  • pt. IV. Genetic association studies
  • Modeling linkage disequilibrium and performing association studies through probabilistic graphical models : a visiting tour of recent advances
  • Modeling linkage disequilibrium with decomposable graphical models
  • Scoring, searching and evaluating Bayesian network models of gene-phenotype association
  • Graphical modeling of biological pathways in genome-wide association studies
  • Bayesian systems-based, multilevel analysis of associations for complex phenotypes : from interpretation to decision
  • pt. V. Epigenetics
  • Bayesian networks in the study of genome-wide DNA methylation
  • Latent variable models for analyzing DNA methylation
  • pt. VI. Detection of copy number variations
  • Detection of copy number variations from array comparative genomic hybridization data using linear-chain conditional random field models
  • pt. VII. Prediction of outcomes from high-dimensional genomic data
  • Prediction of clinical outcomes from genome-wide data.