http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
1 online resource (xv, 280 pages) : illustrations, charts.
This book, Bacteriophages in Health and Disease, is an effort to provide an introduction to the breadth of roles that phages play or can play in our everyday lives. To capture this variety of phage roles in human conditions, both natural and applied, the book is divided into three parts. A brief introduction to various concepts and terminology associated with phages is provided in chapter 1. Part I (chapters 2-6) considers the role of phages in the natural state. That is, where phages are, how they contribute directly to disease, the underlying mechanism by which phages do this, and how they can contribute indirectly to disease, that is, to pathogen evolution. Part II (chapters 7-11) considers various phage-based technologies other than the use of whole phages to combat bacterial infections (i.e. besides phage therapy). This includes in particular the use of both modified and 'disembodied' phage parts. Phages thus can serve as carriers and delivery vehicles of DNA and also of other chemicals, including serving as vectors for either gene therapy or DNA vaccines. Part III (chapters 12-17) covers phage-based antibacterial strategies. It includes chapters on: phage translocation, safety and immunomodulation; phage therapy of wounds and related purulent infections; phage therapy of non-wound infections; phage-based enzybiotics; and phage-based control of bacterial pathogens in food. The final chapter of this book is targeted to would-be phage therapy experimentalists, one that considers, in light of phage properties, how phage therapy protocols may be developed in terms of the use of animal models of bacterial disease.
Phages / Stephen T. Abedon -- Bacteriophages as part of the human microbiome / Andrey V. Letarov -- Diseases caused by phages / Sarah Kuhl, Stephen T. Abedon, and Paul Hyman -- Prophage-induced changes in cellular cytochemistry and virulence / Gail E. Christie, Heather E. Allison, John Kuzio, W. Michael McShan, Matthew K. Waldor and Andrew M. Kropinski -- The lion and the mouse : how bacteriophages create, liberate, and decimate pathogens / Heather Hendrickson -- Phages and bacterial epidemiology / Michele L. Williams and Jeffrey T. LeJeune -- Phages as therapeutic delivery vehicles / Jason Clark, Stephen T. Abedon, and Paul Hyman -- Clinical applications of phage display peptides / Don L. Siegel -- Phages and their hosts : a web of interactions applications to drug design / Jeroen Wagemans and Rob Lavigne -- Bacteriophage-based methods of bacterial detection and identification / Christopher R. Cox -- Phage detection as indication of fecal contamination / Lawrence D. Goodridge and Travis Steiner -- Phage translocation, safety, and immunomodulation / Natasza Olszowska-Zaremba, Jan Borysowski, Krystyna Da̜browska and Andrzej Górski -- Phage therapy of wounds and related purulent infections / Catherine Loc-Carrillo, Sijia Wu, and James Peter Beck -- Phage therapy of non-wound infections / Ben Burrowes and David R. Harper -- Phage-based enzybiotics / Yang Shen, Michael S. Mitchell, David M. Donovan and Daniel C. Nelson -- Role of phages in control of bacterial pathogens in food / Yan D. Niu, Kim Stanford, Tim A. McAllister and Todd R. Callaway -- Phage-therapy best practices / Stephen T. Abedon.
edited by Paul Hyman, Department of Biology/Toxicology, Ashland University and Stephen T. Abedon, Department of Microbiology, The Ohio State University.
Access limited to subscribing institution.
Includes bibliographical references and index.
Biochemistry and Physiology of Microorganisms, (New March 2000)
Diagnostic, Therapeutic and Pharmacological Biotechnology, (New June 2002)
Food Contamination, Residues and Toxicology
Genetic Engineering, Gene Transfer and Transgenics, (New June 2002)
Genetics and Molecular Biology of Microorganisms, (New March 2000)
Molecular Biology and Molecular Genetics, (Discontinued March 2000, Reinstated and Revised June 2002)
Non-drug Therapy and Prophylaxis of Humans, (New March 2000)
Pesticides and Drugs; Control, (New March 2000)
Prion, Viral, Bacterial and Fungal Pathogens of Humans, (New March 2000)
Advances in molecular and cellular microbiology ; 24