Table of Contents:
  • Introduction : the first effective antiviral / Herbert E. Kaufman
  • Discovery and development of zidovudine as the cornerstone of therapy to control human immunodeficiency virus infection / Kathryn H. Pattishall
  • Discovery of nevirapine, a nonnucleoside inhibitor of HIV-1 reverse transcriptase / Julian Adams and Vincent J. Merluzzi
  • Discovery of TIBO, a new family of HIV-1-specific reverse transcriptase inhibitors / Rudi Pauwels
  • Discovery and development of 2-pyridinone HIV-1 reverse transcriptase inhibitors / Mark E. Goldman
  • Discovery and development of the HIV proteinase inhibitor Ro 31-8959 / Noel A. Roberts and Sally Redshaw
  • A new approach to antiviral chemotherapy : intervention in viral gene expression by HIV tat antagonists / Ming-Chu Hsu and Steve Tam
  • Discovery of pirodavir, a broad-spectrum inhibitor of rhinoviruses / Koen Andries
  • sICAM-1 as a receptor antagonist for rhinoviruses : a model system of adhesion molecules as cell receptors for viruses / Steven D. Marlin.
  • (Cont.) Inactivation of herpes simplex virus ribonucleotide reductase by subunit association inhibitors : a potential antiviral strategy / Michel Liuzzi and Robert Déziel.