Form and function of mammalian lung : analysis by scientific computing /
The study approaches the investigations of airway morphology of the lung with a new set of imaging and cmputer graphical methods, including confocal imaging, computer-guided image acquisition, visualization and fractal graphics. The key result is that, in contrast to the belief that the design of th...
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| Format: | eBook |
| Language: | English |
| Published: |
Berlin ; New York :
Springer,
[1998]
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| Series: | Advances in anatomy, embryology, and cell biology ;
v. 145. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | The study approaches the investigations of airway morphology of the lung with a new set of imaging and cmputer graphical methods, including confocal imaging, computer-guided image acquisition, visualization and fractal graphics. The key result is that, in contrast to the belief that the design of the conductive part of the lung of smaller mammals can be decribed with a trumpet model, the findings reported here document a strongly monopodial branching pattern with the functional consequence of a variation of dead space between the trachea and the acini. This non-dichotomic structural design finds its continuation within the respiratory units as the necessary requirement for an optimal space filling and dense packing which cannot be achieved by a dichotomic branching only. Based on a computer model, computational physics tightly coupled with computer visualistics enables functional simulation of the lung model regarding gas transport. The predicted variance in the ventilation of acini gives rise to an explanation of the well-known difference between the morphologically predicted and physiologically required diffusion capacity. |
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| Item Description: | Based on the author's thesis (Habilitationsschrift)--University Clinic Glissen, 1996. Electronic resource. |
| Physical Description: | 1 online resource (ix, 108 pages) : illustrations. |
| Format: | Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. |
| Bibliography: | Includes bibliographical references (pages 99-105) and index. |
| ISBN: | 9783642722202 (electronic bk.) 3642722202 (electronic bk.) |