G proteins, receptors, and disease /

More than a collection of review articles, G Proteins, Receptors, and Disease summarizes in depth the state of our knowledge today concerning not only how cells communicate via G-protein-coupled signal transduction processes, but also how defects in these proteins and their receptors can cause serio...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Spiegel, Allen M.
Format: eBook
Language:English
Published: Totowa, N.J. : Humana Press, [1998]
Series:Contemporary endocrinology (Totowa, N.J.) ; 6.
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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490 1 |a Contemporary endocrinology ;  |v 6 
504 |a Includes bibliographical references and index. 
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520 |a More than a collection of review articles, G Proteins, Receptors, and Disease summarizes in depth the state of our knowledge today concerning not only how cells communicate via G-protein-coupled signal transduction processes, but also how defects in these proteins and their receptors can cause serious human disease involving many different organ systems. Written by leading investigators, each chapter describes in detail the structure and function of a particular G protein or receptor, outlines possible mutations, and discusses fully the molecular pathogenesis of associated diseases. Diagnostic and therapeutic implications are also discussed when relevant. In its unique blend of cutting-edge basic science and clinical medicine, G Proteins, Receptors, and Disease offers deep insights into the physiological significance of this key signal transduction pathway, as well as into the molecular basis of diseases ranging from obesity to malignancy. The basic understanding of the complex signal transduction process achieved here provides a firm foundation for future efforts to prevent and cure these diseases. 
588 |a Description based on print version record. 
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650 0 |a G proteins  |x Physiological effect. 
650 0 |a G proteins  |x Pathophysiology. 
650 0 |a Endocrine glands  |x Diseases. 
650 0 |a Cellular signal transduction. 
650 0 |a Pathology, Molecular. 
650 1 2 |a GTP-Binding Proteins  |x physiology. 
650 2 2 |a Endocrine System Diseases  |x genetics. 
650 2 2 |a Receptors, Cell Surface  |x physiology. 
650 2 2 |a Signal Transduction. 
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