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Ionotropic glutamate receptors in the CNS /

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This volume provides an overview of glutamate receptors and their role in excitatory neurotransmission. It focusses on three aspects. First, it describes the functional, molecular, and pharmacological properties of glutamate receptors (AMPA, NMDA, and kainate receptors). Second, it gives a survey ho...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Adelmann, G., Jonas, Peter, 1961-, Monyer, Hannah, 1957-
Format: eBook
Language:English
Published: Berlin ; New York : Springer, [1999]
Series:Handbook of experimental pharmacology ; v. 141.
Subjects:
Glutamic acid > Receptors.
Excitatory amino acids.
Receptors, Glutamate.
Synaptic Transmission > physiology.
Cell Death > physiology.
Central Nervous System > physiology.
Centraal zenuwstelsel.
Glutamaat.
Neurotransmitters.
Zentralnervensystem.
Glutamatrezeptor.
Zentralnervensystem > Glutamatrezeptor > Aufsatzsammlung
Säugetiere > Zentralnervensystem > Glutamatrezeptor > Aufsatzsammlung
Electronic books.
Aufsatzsammlung.
Online Access:Connect to the full text of this electronic book
Description
Summary:This volume provides an overview of glutamate receptors and their role in excitatory neurotransmission. It focusses on three aspects. First, it describes the functional, molecular, and pharmacological properties of glutamate receptors (AMPA, NMDA, and kainate receptors). Second, it gives a survey how these receptors are involved in synaptic transmission at different glutamatergic synapses in the mammalian CNS. Finally, it adresses how overactivation of glutamate receptors can lead to excitotoxic cell death, and emphasizes the importance of glutamate receptors as potential therapeutical targets. The chapters, written by leading scientists, give accurate summaries of facets that have emerged recently in this field. The book demonstrates the strength of a multidisciplinary approach involving physiology, pharmacology, and molecular biology. It will be useful for other scientists in and outside the field, lecturers and students at different educational levels.
Item Description:Electronic resource.
Physical Description:1 online resource (xxii, 535 pages) : illustrations (some color).
Format:Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Bibliography:Includes bibliographical references and index.
ISBN:9783662080221 (electronic bk.)
3662080222 (electronic bk.)
ISSN:0171-2004 ;