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Stereochemical aspects of drug action and disposition /

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This book aims to guide and inspire drug researchers as they enter the 21st century. Stereochemistry is an essential dimension in pharmacology and should be understood as such by all drug researchers whatever their background. When used as probes or medicines, stereoisomeric drugs offer invaluable i...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Branch, S. K., Eichelbaum, Michel, Testa, Bernard, Somogyi, Andrew
Format: eBook
Language:English
Published: Berlin ; New York : Springer, [2003]
Series:Handbook of experimental pharmacology ; v. 153.
Subjects:
Pharmaceutical chemistry.
Drugs.
Pharmaceutical Preparations > metabolism.
Chemistry, Pharmaceutical.
Drug Interactions.
Stereoisomerism.
Médicaments > Effets physiologiques.
Chimie pharmaceutique.
Médicaments > Analyse.
Stereochemie.
Geneesmiddelen.
Electronic books.
Online Access:Connect to the full text of this electronic book
Description
Summary:This book aims to guide and inspire drug researchers as they enter the 21st century. Stereochemistry is an essential dimension in pharmacology and should be understood as such by all drug researchers whatever their background. When used as probes or medicines, stereoisomeric drugs offer invaluable insights or innovative therapeutic strategies. The book spans the subject from the molecular to the clinical. The first section on chemical aspects contains chapters on chemical synthesis, analysis, natural products, chiral stability (racemezation) and physical properties. The second section is on experimental pharmacology, with chapters on drug-receptor interactions, chiral recognition, ion channels, and molecular toxicology. The third section focuses on drug disposition, with chapters on absorption, distribution, protein binding, metabolism and elimination. The final section is dedicated to regulatory and clinical aspects.
Item Description:Electronic resource.
Physical Description:1 online resource (xxv, 442 pages) : illustrations.
Format:Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Bibliography:Includes bibliographical references and index.
ISBN:9783642558429 (electronic bk.)
3642558429 (electronic bk.)
ISSN:0171-2004 ;