The biology of germinal centers in lymphoid tissue /

This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hyper...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Thorbecke, G. Jeanette, Tsiagbe, Vincent Kwaku
Format: eBook
Language:English
Published: Berlin ; New York : Springer, [1998]
Series:Biotechnology intelligence unit (Unnumbered)
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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245 0 4 |a The biology of germinal centers in lymphoid tissue /  |c [edited by] G. Jeanette Thorbecke, V.K. Tsiagbe. 
264 1 |a Berlin ;  |a New York :  |b Springer,  |c [1998] 
264 4 |c ©1998 
300 |a 1 online resource (239 pages) :  |b illustrations (some color). 
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505 0 |a Overview of germinal center function and structure in normal and genetically engineered mice -- Relationship between the follicular dendritic cell reaction and germinal center development: normal, aged and retrovirus-infected mice -- T and B lymphocytes in germinal centers -- The mechanism of somatic hypermutation of immunoglobulin genes -- Germinal center derived lymphomas in humans and mice.- 
520 |a This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment. 
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650 0 |a Germinal centers. 
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700 1 |a Tsiagbe, Vincent Kwaku. 
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