Immunopathogenesis of HIV infection /

During the last 5 years, major advances have been made in our understanding of the pathogenesis of human immunodeficiency virus (HIV) disease and in the development of new potent antiviral agents. With regard to HIV pathogenesis, several recent observations have not only changed our perspectives of...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Fauci, Anthony S., 1940-, Pantaleo, G. (Giuseppe)
Format: eBook
Language:English
Published: Berlin ; New York : Springer, 1997.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:During the last 5 years, major advances have been made in our understanding of the pathogenesis of human immunodeficiency virus (HIV) disease and in the development of new potent antiviral agents. With regard to HIV pathogenesis, several recent observations have not only changed our perspectives of HIV disease, but have been critical for the design of therapeutic strategies. These oberservations include: 1. The delineation of the virologic and immunologic events associated with primary HIV infection. 2. The development of highly sensitive molecular techniques including polymerase chain reaction (PCR) assays for the determination of HIV RNA in plasma, together with the identification of lymphoid tissue as the primary anatomic site for HIV replication and spreading. 3. The characterization of the dynamics of HIV infection. 4. The identification of chemokines with suppressor activity on HIV replication and the discovery of co-receptor molecules for HIV entry.
Item Description:Electronic resource.
Physical Description:1 online resource (viii, 153 pages) : illustrations (some color)
Format:Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Bibliography:Includes bibliographical references.
ISBN:9783642608674 (electronic bk.)
3642608671 (electronic bk.)